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Anti-CD14 Antibody (6R885) (Synonyms: monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen)

Catalog No. TMAH-00168 Copy Product Info
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Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA,IHC.

Anti-CD14 Antibody (6R885)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00168
Synonyms monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen

Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA,IHC.

Anti-CD14 Antibody
(6R885)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA,IHC.
Synonymsmonocyte differentiation antigen CD14, CD14 molecule, CD14 antigen
Ig Type
hIgG1
Clone
6R885
Reactivity
Human
Verified Activity
IHC image of TMAH-00168 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus.
Tissue SpecificityDetected on macrophages (at protein level). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundCoreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CD14 Protein
Antigen Species
Human
Gene Name
CD14
Gene ID
Uniprot ID
Biology Area
Immunology, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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