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Anti-CD14 Antibody (6R885)
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Catalog No. TMAH-00168
Alias monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen
Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA,IHC.
Anti-CD14 Antibody (6R885)
Anti-CD14 Antibody (6R885)
😃Good
Catalog No. TMAH-00168Alias monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen
Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA,IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD14 Antibody (6R885) is an antibody targeting CD14. Anti-CD14 Antibody (6R885) can be used in ELISA,IHC. |
| Synonyms | monocyte differentiation antigen CD14, CD14 molecule, CD14 antigen |
| Ig Type | hIgG1 |
| Clone | 6R885 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00168 diluted at 1：100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. |
| Tissue Specificity | Detected on macrophages (at protein level). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD14 Protein |
| Antigen Species | Human |
| Gene Name | CD14 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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