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Anti-CBS Antibody (7N696)
😃Good
Catalog No. TMAC-00634
Alias Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase
Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB.
Anti-CBS Antibody (7N696)
Anti-CBS Antibody (7N696)
😃Good
Catalog No. TMAC-00634Alias Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase
Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB. |
| Synonyms | Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase |
| Ig Type | IgG |
| Clone | 7N696 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of CBS on different lysates using anti-CBS antibody at 1/1,000 dilution.Positive control: Lane 1: 293, Lane 2: 293, Lane 3: human liver tissue. 2. ICC staining CBS in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.   |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Strongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are assoc-iated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retard-ation and skeletal abnormalities. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human CBS aa 400-550 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 61 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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