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Anti-CBS Antibody (7N696) (Synonyms: Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase)

Catalog No. TMAC-00634 Copy Product Info
🥰Excellent
Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB.

Anti-CBS Antibody (7N696)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00634
Synonyms Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase

Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB.

Anti-CBS Antibody
(7N696)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB.
SynonymsSerine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase
Ig Type
IgG
Clone
7N696
Reactivity
Human
Verified Activity
1. Western blot analysis of CBS on different lysates using anti-CBS antibody at 1/1,000 dilution.Positive control: Lane 1: 293, Lane 2: 293, Lane 3: human liver tissue.
2. ICC staining CBS in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; ICC: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundStrongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are assoc-iated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retard-ation and skeletal abnormalities.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human CBS aa 400-550
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 61 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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