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Anti-ICOS Antibody (4Y416)
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Catalog No. TMAB-07483 Copy Product Info
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Anti-ICOS Antibody (4Y416) is a Rabbit antibody targeting ICOS. Anti-ICOS Antibody (4Y416) can be used in WB,ICC/IF,FCM.
Anti-ICOS Antibody
(4Y416)
(4Y416)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ICOS Antibody (4Y416) is a Rabbit antibody targeting ICOS. Anti-ICOS Antibody (4Y416) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 4Y416 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200; FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential).Isoform 2: Secreted (Potential). |
| Tissue Specificity | Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B-cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.[provided by RefSeq, Jul 2008]. |
| Immunogen | A synthesized peptide: human ICOS |
| Antigen Species | Human |
| Gene Name | ICOS |
| Gene ID | |
| Protein Name | Inducible T-cell costimulator |
| Uniprot ID | |
| Function | Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity). |
| Molecular Weight | Theoretical: 20 kDa. Actual: 23 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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