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Anti-BBC3/PUMA Antibody (4W275)
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Catalog No. TMAB-03032
Anti-BBC3/PUMA Antibody (4W275) is a Rabbit antibody targeting BBC3/PUMA. Anti-BBC3/PUMA Antibody (4W275) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Anti-BBC3/PUMA Antibody (4W275)
Anti-BBC3/PUMA Antibody (4W275)
😃Good
Catalog No. TMAB-03032
Anti-BBC3/PUMA Antibody (4W275) is a Rabbit antibody targeting BBC3/PUMA. Anti-BBC3/PUMA Antibody (4W275) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-BBC3/PUMA Antibody (4W275) is a Rabbit antibody targeting BBC3/PUMA. Anti-BBC3/PUMA Antibody (4W275) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| Clone | 4W275 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis.Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis. |
| Immunogen | A synthesized peptide: human BBC3 |
| Antigen Species | Human |
| Gene Name | BBC3 |
| Gene ID | |
| Protein Name | Bcl-2-binding component 3, isoforms 1/2 |
| Uniprot ID | |
| Function | Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Essential for ER stress-induced cell death. |
| Molecular Weight | Theoretical: 21 kDa. Actual: 18 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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