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Anti-CD20 Antibody (9T986) is a Rabbit antibody targeting CD20. Anti-CD20 Antibody (9T986) can be used in WB,IHC,IP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-CD20 Antibody (9T986) is a Rabbit antibody targeting CD20. Anti-CD20 Antibody (9T986) can be used in WB,IHC,IP. |
Synonyms | MS4A-1, MS4A1, Membrane-spanning 4-domains subfamily A member 11, Leukocyte surface antigen Leu-16, CD20, Bp35, B-lymphocyte surface antigen B1 |
Ig Type | IgG |
Reactivity | Human,Monkey |
Verified Activity | 1. Western blot analysis of CD20 on Raji cell lysates using anti-CD20 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD20 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD20 antibody. Counter stained with hematoxylin. |
Application | |
Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 33 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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