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Anti-ALOX5AP Antibody (8Z112)

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Catalog No. TMAB-02450

Anti-ALOX5AP Antibody (8Z112) is a Rabbit antibody targeting ALOX5AP. Anti-ALOX5AP Antibody (8Z112) can be used in WB.

Anti-ALOX5AP Antibody (8Z112)

Anti-ALOX5AP Antibody (8Z112)

Copy Product Info
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Catalog No. TMAB-02450
Anti-ALOX5AP Antibody (8Z112) is a Rabbit antibody targeting ALOX5AP. Anti-ALOX5AP Antibody (8Z112) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ALOX5AP Antibody (8Z112) is a Rabbit antibody targeting ALOX5AP. Anti-ALOX5AP Antibody (8Z112) can be used in WB.
Ig Type
IgG
Clone
8Z112
Reactivity
Human
Verified Activity
THP-1 (H) cells were treated with or without PMA (80 nM) for 72 h, 25 μg total protein per lane of cell lysates (see on figure) probed with ALOX5AP monoclonal antibody, unconjugated (TMAB-02450) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundRequired for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Antigen Details
Immunogen
A synthesized peptide: human FLAP
Antigen Species
Human
Gene Name
ALOX5AP
Gene ID
Protein Name
Arachidonate 5-lipoxygenase-activating protein
Uniprot ID
Function
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Chemical Properties
Molecular WeightTheoretical: 18 kDa. Actual: 16 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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