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Anti-ALOX5AP Antibody (8Z112) is a Rabbit antibody targeting ALOX5AP. Anti-ALOX5AP Antibody (8Z112) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-ALOX5AP Antibody (8Z112) is a Rabbit antibody targeting ALOX5AP. Anti-ALOX5AP Antibody (8Z112) can be used in WB. |
| Ig Type | IgG |
| Clone | 8Z112 |
| Reactivity | Human |
| Verified Activity | THP-1 (H) cells were treated with or without PMA (80 nM) for 72 h, 25 μg total protein per lane of cell lysates (see on figure) probed with ALOX5AP monoclonal antibody, unconjugated (TMAB-02450) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
| Immunogen | A synthesized peptide: human FLAP |
| Antigen Species | Human |
| Gene Name | ALOX5AP |
| Gene ID | |
| Protein Name | Arachidonate 5-lipoxygenase-activating protein |
| Uniprot ID | |
| Function | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
| Molecular Weight | Theoretical: 18 kDa. Actual: 16 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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