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Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi)

TargetMol | SPR
Catalog No. TMPY-05716U

Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3).

Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi)

Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi)

TargetMol | SPR
Catalog No. TMPY-05716U
Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 μg$617-10 days7-10 days
10 μg$977-10 days7-10 days
20 μg$1587-10 days7-10 days
50 μg$2977-10 days7-10 days
100 μg$5177-10 days7-10 days
200 μg$9137-10 days7-10 days
500 μg$1,9307-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Product Information

Biological Activity
Immobilized Human ITGAV&ITGB3, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 9.2 ng/ml determined by ELISA.
Description
Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3).
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP06756-1(ITGAV)&P05106-1(ITGB3)
Synonyms
Integrin α V β 3,Integrin alpha V β3
Construction
Phe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight114 kDa (ITGAV) & 81.3 kDa (ITGB3) (Predicted); 85-140 kDa (Due to glycosylation)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

Dose Conversion

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Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

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