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Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $61 | 7-10 days | 7-10 days | |
| 10 μg | $97 | 7-10 days | 7-10 days | |
| 20 μg | $158 | 7-10 days | 7-10 days | |
| 50 μg | $297 | 7-10 days | 7-10 days | |
| 100 μg | $517 | 7-10 days | 7-10 days | |
| 200 μg | $913 | 7-10 days | 7-10 days | |
| 500 μg | $1,930 | 7-10 days | 7-10 days |
| Biological Activity | Immobilized Human ITGAV&ITGB3, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 9.2 ng/ml determined by ELISA. |
| Description | Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3). |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | P06756-1(ITGAV)&P05106-1(ITGB3) |
| Synonyms | Integrin α V β 3,Integrin alpha V β3 |
| Construction | Phe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Molecular Weight | 114 kDa (ITGAV) & 81.3 kDa (ITGB3) (Predicted); 85-140 kDa (Due to glycosylation) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
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