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Anti-MEF2A Antibody (1G264)

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Catalog No. TMAB-08714

Anti-MEF2A Antibody (1G264) is a Rabbit antibody targeting MEF2A. Anti-MEF2A Antibody (1G264) can be used in WB,ICC/IF,IHC-P,IHC-Fr,IF.

Anti-MEF2A Antibody (1G264)

Anti-MEF2A Antibody (1G264)

😃Good
Catalog No. TMAB-08714
Anti-MEF2A Antibody (1G264) is a Rabbit antibody targeting MEF2A. Anti-MEF2A Antibody (1G264) can be used in WB,ICC/IF,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MEF2A Antibody (1G264) is a Rabbit antibody targeting MEF2A. Anti-MEF2A Antibody (1G264) can be used in WB,ICC/IF,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1G264
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; ICC/IF: 1:50-200; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityIsoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Antigen Details
Immunogen
A synthesized peptide: human MEF2A
Antigen Species
Human
Gene Name
MEF2A
Gene ID
Protein Name
Myocyte-specific enhancer factor 2A
Uniprot ID
Function
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.
Chemical Properties
Molecular WeightTheoretical: 55 kDa. Actual: 55 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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