IL-9 Protein, Mouse, Recombinant (HEK293, His)

Catalog No. TMPY-05221U

IL-9 Protein, Mouse, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P15247.

IL-9 Protein, Mouse, Recombinant (HEK293, His)

Catalog No. TMPY-05221U

IL-9 Protein, Mouse, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P15247.

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Biological Activity	Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is < 3 ng/mL.
Description	IL-9 Protein, Mouse, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P15247.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P15247
Synonyms	P40,interleukin 9,Il-9
Construction	Gln19-Pro144
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	15.4 kDa (Predicted); 40-50 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.