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Anti-CENPC1 Antibody (8J653)
😃Good
Catalog No. TMAB-04225
Anti-CENPC1 Antibody (8J653) is a Rabbit antibody targeting CENPC1. Anti-CENPC1 Antibody (8J653) can be used in WB,ICC/IF.
Anti-CENPC1 Antibody (8J653)
Anti-CENPC1 Antibody (8J653)
😃Good
Catalog No. TMAB-04225
Anti-CENPC1 Antibody (8J653) is a Rabbit antibody targeting CENPC1. Anti-CENPC1 Antibody (8J653) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CENPC1 Antibody (8J653) is a Rabbit antibody targeting CENPC1. Anti-CENPC1 Antibody (8J653) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 8J653 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. |
| Immunogen | A synthesized peptide: human CENPC |
| Antigen Species | Human |
| Gene Name | CENPC |
| Gene ID | |
| Protein Name | Centromere protein C |
| Uniprot ID | |
| Function | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. |
| Molecular Weight | Theoretical: 107 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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