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Anti-CD45 Antibody (4V471)
😃Good
Catalog No. TMAH-00203
Alias T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220
Anti-CD45 Antibody (4V471) is an antibody targeting CD45. Anti-CD45 Antibody (4V471) can be used in ELISA.
Anti-CD45 Antibody (4V471)
Anti-CD45 Antibody (4V471)
😃Good
Catalog No. TMAH-00203Alias T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220
Anti-CD45 Antibody (4V471) is an antibody targeting CD45. Anti-CD45 Antibody (4V471) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Chemical Properties
| Description | Anti-CD45 Antibody (4V471) is an antibody targeting CD45. Anti-CD45 Antibody (4V471) can be used in ELISA. |
| Synonyms | T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220 |
| Ig Type | Rabbit IgG |
| Clone | 4V471 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Membrane raft. |
| Tissue Specificity | Isoform 1: Detected in thymocytes. Isoform 2: Detected in thymocytes. Isoform 3: Detected in thymocytes. Isoform 4: Not detected in thymocytes. Isoform 5: Detected in thymocytes. Isoform 6: Not detected in thymocytes. Isoform 7: Detected in thymocytes. Is |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide |
| Antigen Species | Human |
| Gene Name | PTPRC |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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