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Anti-GTF2I Antibody (1N779)

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Catalog No. TMAB-06843 Copy Product Info
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Anti-GTF2I Antibody (1N779) is a Rabbit antibody targeting GTF2I. Anti-GTF2I Antibody (1N779) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-GTF2I Antibody
(1N779)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GTF2I Antibody (1N779) is a Rabbit antibody targeting GTF2I. Anti-GTF2I Antibody (1N779) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
1N779
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
FCM=1:50-100; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Colocalizes with BTK in the cytoplasm.
Tissue SpecificityUbiquitous. Isoform 1 is strongly expressed in fetal brain, weakly in adult brain, muscle, and lymphoblasts and is almost undetectable in other adult tissues, while the other isoforms are equally expressed in all adult tissues.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInteracts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes.
Antigen Details
Immunogen
A synthesized peptide: human GTF2I
Antigen Species
Human
Gene Name
GTF2I
Gene ID
Protein Name
General transcription factor II-I
Uniprot ID
Function
Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.
Chemical Properties
Molecular WeightTheoretical: 112 kDa. Actual: 135-138 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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