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GM-CSFR alpha Protein, Human, Recombinant (His) V2
(Synonyms: SMDP4, GMR, GM-CSF-R-α, GM-CSF-R-alpha, GMCSFR, GM-CSF Receptor α Protein, CSF2RY, CSF2RX, CSF2RAY, CSF2RAX, CSF2R, colony stimulating factor 2 receptor, α, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CDw116, CD116) Copy Product InfoSynonyms: SMDP4, GMR, GM-CSF-R-α, GM-CSF-R-alpha, GMCSFR, GM-CSF Receptor α Protein, CSF2RY, CSF2RX, CSF2RAY, CSF2RAX, CSF2R, colony stimulating factor 2 receptor, α, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CDw116, CD116
Catalog No. TMPY-01065U Copy Product Info
GM-CSFR alpha Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P15509.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $70 | 7-10 days | 7-10 days | |
| 10 µg | $109 | 7-10 days | 7-10 days | |
| 20 µg | $182 | 7-10 days | 7-10 days | |
| 50 µg | $357 | 7-10 days | 7-10 days | |
| 100 µg | $600 | 7-10 days | 7-10 days | |
| 200 µg | $1,050 | 7-10 days | 7-10 days | |
| 500 µg | $2,190 | 7-10 days | 7-10 days | |
| 1 mg | $3,910 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to inhibit GM-CSF-dependent proliferation of TF‑1 human erythroleukemic cells.The ED50 for this effect is 0.5-2 μg/ml. (QC verified) |
| Description | GM-CSFR alpha Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P15509. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | P15509 |
| Construction | Glu23-Gly320 |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | SMDP4, GMR, GM-CSF-R-α, GM-CSF-R-alpha, GMCSFR, GM-CSF Receptor α Protein, CSF2RY, CSF2RX, CSF2RAY, CSF2RAX, CSF2R, colony stimulating factor 2 receptor, α, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CDw116, CD116 |
| Research Background | Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4). |
| Molecular Weight | 35.5 kDa (Predicted); 60 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: GM-CSFR alpha Protein, Human, Recombinant (His) V2 chemical structure | GM-CSFR alpha Protein, Human, Recombinant (His) V2 molecular weight
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