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GDF-15 Protein, Human, Recombinant (E. coli, His)
(Synonyms: PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15) Copy Product InfoSynonyms: PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Catalog No. TMPY-04727U Copy Product Info
GDF-15 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. The accession number is Q99988-1.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $44 | 7-10 days | 7-10 days | |
| 10 µg | $68 | 7-10 days | 7-10 days | |
| 20 µg | $108 | 7-10 days | 7-10 days | |
| 50 µg | $198 | 7-10 days | 7-10 days | |
| 100 µg | $346 | 7-10 days | 7-10 days | |
| 200 µg | $585 | 7-10 days | 7-10 days | |
| 500 µg | $1,160 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human GDF15, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 11.5 ng/ml determined by ELISA. Human GFRAL, hFc Tag captured on CM5 Chip via Protein A can bind Human GDF15, His Tag with an affinity constant of 0.014 nM as determined in SPR assay (Biacore T200). |
| Description | GDF-15 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. The accession number is Q99988-1. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-His |
| Accession Number | Q99988-1 |
| Construction | Ala197-Ile308 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in 50 mM HAc (pH 2.9). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15 |
| Research Background | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |
| Molecular Weight | 13.5 kDa (Predicted); 15-16 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: GDF-15 Protein, Human, Recombinant (E. coli, His) chemical structure | GDF-15 Protein, Human, Recombinant (E. coli, His) molecular weight
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