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Anti-MGEA5 Antibody (8U249) is a Rabbit antibody targeting MGEA5. Anti-MGEA5 Antibody (8U249) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
| Description | Anti-MGEA5 Antibody (8U249) is a Rabbit antibody targeting MGEA5. Anti-MGEA5 Antibody (8U249) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 8U249 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM=1:50-100; IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 3: Nucleus. Isoform 1: Cytoplasm. |
| Tissue Specificity | Ubiquitous. Shows highest expression in the brain, placenta and pancreas. [PTM] Proteolytically cleaved by caspase-3. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Isoform 3: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins.Isoform 3 Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. |
| Immunogen | A synthesized peptide: human OGA |
| Antigen Species | Human |
| Gene Name | OGA |
| Gene ID | |
| Protein Name | Protein O-GlcNAcase |
| Uniprot ID | |
| Function | Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3 (By similarity). |
| Molecular Weight | Theoretical: 103 kDa. Actual: 130 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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