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Anti-ATG4A Antibody (2N859)
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Catalog No. TMAB-02919
Anti-ATG4A Antibody (2N859) is a Rabbit antibody targeting ATG4A. Anti-ATG4A Antibody (2N859) can be used in WB,IHC-P,IHC-Fr,IP,IF,ICC/IF,FCM.
Anti-ATG4A Antibody (2N859)
Anti-ATG4A Antibody (2N859)
😃Good
Catalog No. TMAB-02919
Anti-ATG4A Antibody (2N859) is a Rabbit antibody targeting ATG4A. Anti-ATG4A Antibody (2N859) can be used in WB,IHC-P,IHC-Fr,IP,IF,ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ATG4A Antibody (2N859) is a Rabbit antibody targeting ATG4A. Anti-ATG4A Antibody (2N859) can be used in WB,IHC-P,IHC-Fr,IP,IF,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 2N859 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IP: 1:20-50; IF: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm (Probable). |
| Tissue Specificity | Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine. |
| Immunogen | A synthesized peptide: human Cysteine protease ATG4A |
| Antigen Species | Human |
| Gene Name | ATG4A |
| Gene ID | |
| Protein Name | Cysteine protease ATG4A |
| Uniprot ID | |
| Function | Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. |
| Molecular Weight | Theoretical: 45 kDa. Actual: 45 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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