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Anti-RALBP1 Antibody (8I172)
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Catalog No. TMAB-12062 Copy Product Info
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Anti-RALBP1 Antibody (8I172) is a Rabbit antibody targeting RALBP1. Anti-RALBP1 Antibody (8I172) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Anti-RALBP1 Antibody
(8I172)
(8I172)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-RALBP1 Antibody (8I172) is a Rabbit antibody targeting RALBP1. Anti-RALBP1 Antibody (8I172) can be used in FCM, IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 8I172 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane, Peripheral membrane protein. |
| Tissue Specificity | Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Multifunctional protein that functions as a downstream effector of RALA and RALB.As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity.As part of the Ral signaling pathway, may also regulate ligand-dependent EGF and insulin receptors-mediated endocytosis. |
| Immunogen | A synthesized peptide: human RalBP1 |
| Antigen Species | Human |
| Gene Name | RALBP1 |
| Gene ID | |
| Protein Name | RalA-binding protein 1 |
| Uniprot ID | |
| Function | Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. |
| Molecular Weight | Theoretical: 76 kDa. Actual: 98 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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