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Anti-NFATc2 Antibody (4P455)

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Catalog No. TMAB-09426 Copy Product Info
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Anti-NFATc2 Antibody (4P455) is a Rabbit antibody targeting NFATc2. Anti-NFATc2 Antibody (4P455) can be used in WB.
Anti-NFATc2 Antibody
(4P455)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NFATc2 Antibody (4P455) is a Rabbit antibody targeting NFATc2. Anti-NFATc2 Antibody (4P455) can be used in WB.
Ig Type
IgG
Clone
4P455
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Tissue SpecificityExpressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPlays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF.
Antigen Details
Immunogen
A synthesized peptide: human NFATc2
Antigen Species
Human
Gene Name
NFATC2
Gene ID
Protein Name
Nuclear factor of activated T-cells, cytoplasmic 2
Uniprot ID
Function
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
Chemical Properties
Molecular WeightTheoretical: 100 kDa. Actual: 130 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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