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Anti-PCSK9 Antibody (6M447) is a Rabbit antibody targeting PCSK9. Anti-PCSK9 Antibody (6M447) can be used in WB,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-PCSK9 Antibody (6M447) is a Rabbit antibody targeting PCSK9. Anti-PCSK9 Antibody (6M447) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 6M447 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. |
| Immunogen | A synthesized peptide: human PCSK9 |
| Antigen Species | Human |
| Gene Name | PCSK9 |
| Gene ID | |
| Protein Name | Proprotein convertase subtilisin/kexin type 9 |
| Uniprot ID | |
| Function | The precursor protein but not the mature protein may form multimers. |
| Molecular Weight | Theoretical: 74 kDa. Actual: 62, 78 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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