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Anti-Islet-1 Antibody (4F162) is a Rabbit antibody targeting Islet-1. Anti-Islet-1 Antibody (4F162) can be used in WB,ICC/IF,IP,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-Islet-1 Antibody (4F162) is a Rabbit antibody targeting Islet-1. Anti-Islet-1 Antibody (4F162) can be used in WB,ICC/IF,IP,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 4F162 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. |
| Immunogen | A synthesized peptide: human Islet 1 |
| Antigen Species | Human |
| Gene Name | ISL1 |
| Gene ID | |
| Protein Name | Insulin gene enhancer protein ISL-1 |
| Uniprot ID | |
| Function | Binds to one of the cis-acting domain of the insulin gene enhancer. |
| Molecular Weight | Theoretical: 39 kDa. Actual: 39 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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