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Anti-GRM2 Antibody (7A975)

Catalog No. TMAB-06791 Copy Product Info
🥰Excellent
Anti-GRM2 Antibody (7A975) is a Rabbit antibody targeting GRM2. Anti-GRM2 Antibody (7A975) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.

Anti-GRM2 Antibody (7A975)

Copy Product Info
🥰Excellent
Catalog No. TMAB-06791

Anti-GRM2 Antibody (7A975) is a Rabbit antibody targeting GRM2. Anti-GRM2 Antibody (7A975) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.

Anti-GRM2 Antibody
(7A975)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GRM2 Antibody (7A975) is a Rabbit antibody targeting GRM2. Anti-GRM2 Antibody (7A975) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
7A975
Reactivity
Human,Mouse,Rat
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with GRM2 Monoclonal Antibody, Unconjugated (TMAB-06791) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with GRM2 Monoclonal Antibody, Unconjugated (TMAB-06791) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with GRM2 Monoclonal Antibody, Unconjugated (TMAB-06791) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with GRM2 Monoclonal Antibody, Unconjugated (TMAB-06791) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Rat Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with GRM2 Monoclonal Antibody, Unconjugated (TMAB-06791) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with GRM2 Monoclonal Antibody, Unconjugated (TMAB-06791) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
Application
Recommended Dose
ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityWidely expressed in different regions of the adult brain as well as in fetal brain.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundG-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Antigen Details
Immunogen
A synthesized peptide: human mGluR2
Antigen Species
Human
Gene Name
GRM2
Gene ID
Protein Name
Metabotropic glutamate receptor 2
Uniprot ID
Function
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Chemical Properties
Molecular WeightTheoretical: 96 kDa. Actual: 95, 200 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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