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Anti-delta 2 Catenin Antibody (8O145)

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Catalog No. TMAB-05071

Anti-delta 2 Catenin Antibody (8O145) is a Rabbit antibody targeting delta 2 Catenin. Anti-delta 2 Catenin Antibody (8O145) can be used in WB, ICC/IF, FCM.

Anti-delta 2 Catenin Antibody (8O145)

Anti-delta 2 Catenin Antibody (8O145)

Copy Product Info
😃Good
Catalog No. TMAB-05071
Anti-delta 2 Catenin Antibody (8O145) is a Rabbit antibody targeting delta 2 Catenin. Anti-delta 2 Catenin Antibody (8O145) can be used in WB, ICC/IF, FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-delta 2 Catenin Antibody (8O145) is a Rabbit antibody targeting delta 2 Catenin. Anti-delta 2 Catenin Antibody (8O145) can be used in WB, ICC/IF, FCM.
Ig Type
IgG
Clone
8O145
Reactivity
Mouse,Rat,Human
Verified Activity
1. The SH-SY5Y (H) cells were fixed with 4% PFA (10 min at r. T.) and then permeabilized with 90% ice-cold methanol for 20 min at -20℃, the cells then were incubated in 5% BSA to block non-specific protein-protein interactions (30 min at r. T.), followed by secondary antibody incubation for 40 min at room temperature. Primary Antibody (green): Rabbit Anti-delta 2 Catenin antibody (TMAB-05071, 1: 100); Isotype Control (orange): Rabbit IgG. Blank control (black): PBS. Acquisition of 20,000 events was performed.
2. 25 ug total protein per lane of various lysates (see on figure) probed with delta 2 Catenin monoclonal antibody, unconjugated (TMAB-05071) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityPredominantly expressed in brain.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundHas a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses. Involved in the regulation of canonical Wnt signaling.It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation.
Antigen Details
Immunogen
A synthesized peptide: mouse delta 2 Catenin
Antigen Species
Mouse
Gene Name
CTNND2
Gene ID
Protein Name
Catenin delta-2
Uniprot ID
Function
Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.
Chemical Properties
Molecular WeightTheoretical: 135 kDa. Actual: 135 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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