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Anti-Cyclin E1 Antibody (1V718)
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Catalog No. TMAB-04835
Anti-Cyclin E1 Antibody (1V718) is a Rabbit antibody targeting Cyclin E1. Anti-Cyclin E1 Antibody (1V718) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Anti-Cyclin E1 Antibody (1V718)
Anti-Cyclin E1 Antibody (1V718)
😃Good
Catalog No. TMAB-04835
Anti-Cyclin E1 Antibody (1V718) is a Rabbit antibody targeting Cyclin E1. Anti-Cyclin E1 Antibody (1V718) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cyclin E1 Antibody (1V718) is a Rabbit antibody targeting Cyclin E1. Anti-Cyclin E1 Antibody (1V718) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Clone | 1V718 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
| Immunogen | A synthesized peptide: human Cyclin E1 |
| Antigen Species | Human |
| Gene Name | CCNE1 |
| Gene ID | |
| Protein Name | G1/S-specific cyclin-E1 |
| Uniprot ID | |
| Function | Essential for the control of the cell cycle at the G1/S (start) transition. |
| Molecular Weight | Theoretical: 45 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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