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IL-13 Protein, Human, Recombinant (E. coli)

(Synonyms: P600, interleukin 13, IL-13, ALRH) Copy Product Info

Synonyms: P600, interleukin 13, IL-13, ALRH

Catalog No. TMPY-01993U Copy Product Info
IL-13 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is AAK53823.
IL-13 Protein, Human, Recombinant (E. coli)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$66-In Stock
10 µg$987-10 days7-10 days
20 µg$165-In Stock
50 µg$3157-10 days7-10 days
100 µg$518-In Stock
200 µg$9177-10 days7-10 days
500 µgPreferential7-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.5-3 ng/mL. (QC Test)
Immobilized Human IL-13, No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 3.6 ng/ml determined by ELISA. (QC Test)
Loaded Human IL-13Ra2, His Tag on Anti-His-Biosensor can bind Human IL-13, No Tag with an affinity constant of 0.63 nM as determined in BLI assay (Gator® Prime).
Description
IL-13 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is AAK53823.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberAAK53823
ConstructionGly21-Asn132
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin< 0.1 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsP600, interleukin 13, IL-13, ALRH
Research Background
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Chemical Properties
Molecular Weight12.34 kDa (Predicted and reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: IL-13 Protein, Human, Recombinant (E. coli) chemical structure | IL-13 Protein, Human, Recombinant (E. coli) molecular weight