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IL-8/CXCL8 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P10145-1.

| Pack Size | Price | Availability | Quantity | 
|---|
| Biological Activity | Immobilized Human IL-8, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-IL-8 Antibody, hFc Tag with the EC50 of 12.5 ng/ml determined by ELISA. | 
| Description | IL-8/CXCL8 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is P10145-1. | 
| Species | Human | 
| Expression System | HEK293 Cells | 
| Tag | C-His | 
| Accession Number | P10145-1 | 
| Synonyms | NAP-1,NAP1,NAF,MONAP,MDNCF,LYNAP,LUCT,LECT,Interleukin-8,IL-8,IL8,GCP-1,GCP1,chemokine (C-X-C motif) ligand 8 | 
| Construction | Ser28-Ser99 | 
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC | 
| Molecular Weight | 9.5 kDa (Predicted); 11-13 kDa (Due to glycosylation) | 
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. | 
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| Research Background | Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms. | 

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