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Anti-B2M/beta 2-Microglobulin Antibody (1O957)

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Catalog No. TMAC-00421

Anti-B2M/beta 2-Microglobulin Antibody (1O957) is a Rabbit antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody (1O957) can be used in WB,ICC,IP.

Anti-B2M/beta 2-Microglobulin Antibody (1O957)

Anti-B2M/beta 2-Microglobulin Antibody (1O957)

😃Good
Catalog No. TMAC-00421
Anti-B2M/beta 2-Microglobulin Antibody (1O957) is a Rabbit antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody (1O957) can be used in WB,ICC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-B2M/beta 2-Microglobulin Antibody (1O957) is a Rabbit antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody (1O957) can be used in WB,ICC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMajor histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an a heavy chain that contains three subdomains (α1, α2, α3), and a non-covalent associating light chain, known as β-2-Microglobulin. β-2-Microglobulin associates with the a3 subdomain of the a heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The α1 and α2 domains of the a heavy chain form the peptide antigen-binding cleft. Mice that lack β-2-Microglobulin protein show a normal distribution of T cells, yet have no mature CD4-8+ T cells and are defective in CD4-8+ T cell-mediated cytotoxicity. Interferon-γ can stimulate production of β-2-Microglobulin transcripts. The human β-2-Microglobulin gene maps to chromosome 15q21-q22.2 and encodes a 119 amino acid protein. Mutations in the β-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 14 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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