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Anti-NRAS Antibody (8O77)

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Catalog No. TMAC-03537

Anti-NRAS Antibody (8O77) is a Rabbit antibody targeting NRAS. Anti-NRAS Antibody (8O77) can be used in WB,IP,FCM.

Anti-NRAS Antibody (8O77)

Anti-NRAS Antibody (8O77)

😃Good
Catalog No. TMAC-03537
Anti-NRAS Antibody (8O77) is a Rabbit antibody targeting NRAS. Anti-NRAS Antibody (8O77) can be used in WB,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-NRAS Antibody (8O77) is a Rabbit antibody targeting NRAS. Anti-NRAS Antibody (8O77) can be used in WB,IP,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat,zebrafish
Application
Recommended Dose
WB: 1:1000-5000; FCM: 1:10-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRas superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 18 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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