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Anti-ACE Antibody (9K374)
😃Good
Catalog No. TMAH-00005
Alias Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme
Anti-ACE Antibody (9K374) is an antibody targeting ACE. Anti-ACE Antibody (9K374) can be used in ELISA,IHC.
Anti-ACE Antibody (9K374)
Anti-ACE Antibody (9K374)
😃Good
Catalog No. TMAH-00005Alias Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme
Anti-ACE Antibody (9K374) is an antibody targeting ACE. Anti-ACE Antibody (9K374) can be used in ELISA,IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ACE Antibody (9K374) is an antibody targeting ACE. Anti-ACE Antibody (9K374) can be used in ELISA,IHC. |
| Synonyms | Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme |
| Ig Type | Rabbit IgG |
| Clone | 9K374 |
| Reactivity | Human |
| Verified Activity | 1. IHC image of TMAH-00005 diluted at 1:100 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00005 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Angiotensin-converting enzyme, soluble form]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm. |
| Tissue Specificity | Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ACE1 |
| Antigen Species | Human |
| Gene Name | ACE |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Cell biology, Metabolism, Signal transduction, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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