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Anti-ACE Antibody (9K374) (Synonyms: Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD a...)

Catalog No. TMAH-00005 Copy Product Info
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Anti-ACE Antibody (9K374) is an antibody targeting ACE. Anti-ACE Antibody (9K374) can be used in ELISA,IHC.

Anti-ACE Antibody (9K374)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00005
Synonyms Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme

Anti-ACE Antibody (9K374) is an antibody targeting ACE. Anti-ACE Antibody (9K374) can be used in ELISA,IHC.

Anti-ACE Antibody
(9K374)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ACE Antibody (9K374) is an antibody targeting ACE. Anti-ACE Antibody (9K374) can be used in ELISA,IHC.
SynonymsKininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme
Ig Type
Rabbit IgG
Clone
9K374
Reactivity
Human
Verified Activity
1. IHC image of TMAH-00005 diluted at 1:100 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
2. IHC image of TMAH-00005 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular Localization[Angiotensin-converting enzyme, soluble form]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Tissue SpecificityUbiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundConverts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human ACE1
Antigen Species
Human
Gene Name
ACE
Gene ID
Uniprot ID
Biology Area
Cancer, Cardiovascular, Cell biology, Metabolism, Signal transduction, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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