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Anti-Pumilio 1 Antibody (6U252)

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Catalog No. TMAB-11946

Anti-Pumilio 1 Antibody (6U252) is a Rabbit antibody targeting Pumilio 1. Anti-Pumilio 1 Antibody (6U252) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.

Anti-Pumilio 1 Antibody (6U252)

Anti-Pumilio 1 Antibody (6U252)

😃Good
Catalog No. TMAB-11946
Anti-Pumilio 1 Antibody (6U252) is a Rabbit antibody targeting Pumilio 1. Anti-Pumilio 1 Antibody (6U252) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Pumilio 1 Antibody (6U252) is a Rabbit antibody targeting Pumilio 1. Anti-Pumilio 1 Antibody (6U252) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
Clone
6U252
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IHC-Fr
ICC/IF
IF
IP
FCM
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm (Probable).
Tissue SpecificityExpressed in brain, heart, kidney, muscle, intestine and stomach. Not expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundSequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE).Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation.
Antigen Details
Immunogen
A synthesized peptide: human Pumilio 1
Antigen Species
Human
Gene Name
PUM1
Gene ID
9698
Protein Name
Pumilio homolog 1
Uniprot ID
Q14671
Function
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
Chemical Properties
Molecular WeightTheoretical: 126 kDa. Actual: 140 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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