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IL-22 Protein, Human, Recombinant (E. coli)

(Synonyms: zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22) Copy Product Info

Synonyms: zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22

Catalog No. TMPY-03490U Copy Product Info
IL-22 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is Q9GZX6.
IL-22 Protein, Human, Recombinant (E. coli)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$136-In Stock
10 µg$218-In Stock
20 µg$348-In Stock
50 µg$627-In Stock
100 µg$998-In Stock
200 µg$1,610-In Stock
500 µg$2,8907-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 98% as analyzed by SDS-PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The ED50 for this effect is less than 1.0 ng/ml.
Description
IL-22 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is Q9GZX6.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberQ9GZX6
ConstructionAla34-Ile179 Expressed with an N-terminal Met
Protein Purity
> 98% as determined by SDS-PAGE
Endotoxin< 0.2 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonymszcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22
Research Background
Interleukin-22(IL-22) belongs to a group of cytokines called the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26) which are a class of potent mediators of cellular inflammatory responses. It shares use of IL-10R2 in cell signaling with other members of this family, such as IL-10, IL-26, IL-28A/B and IL-29. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens in epithelial cells such as those in the lung and gut. IL-22 along with IL-17 is produced by splenic LTi-like cells and Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
Chemical Properties
Molecular Weight16.9 kDa (Reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: IL-22 Protein, Human, Recombinant (E. coli) chemical structure | IL-22 Protein, Human, Recombinant (E. coli) molecular weight