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Anti-LGALS3 Antibody (1Z486) (Synonyms: MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, G...)

Catalog No. TMAC-01597 Copy Product Info
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Anti-LGALS3 Antibody (1Z486) is a Rabbit antibody targeting LGALS3. Anti-LGALS3 Antibody (1Z486) can be used in FCM,ICC/IF,WB.

Anti-LGALS3 Antibody (1Z486)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01597
Synonyms MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3

Anti-LGALS3 Antibody (1Z486) is a Rabbit antibody targeting LGALS3. Anti-LGALS3 Antibody (1Z486) can be used in FCM,ICC/IF,WB.

Anti-LGALS3 Antibody
(1Z486)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LGALS3 Antibody (1Z486) is a Rabbit antibody targeting LGALS3. Anti-LGALS3 Antibody (1Z486) can be used in FCM,ICC/IF,WB.
SynonymsMAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3
Ig Type
IgG
Clone
1Z486
Reactivity
Human,Rat
Verified Activity
1. Western blot analysis of Galectin 3 on different lysates using anti-Galectin 3 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: NIH/3T3, Lane 3: THP-1.
2. ICC staining Galectin 3 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Galectin 3 in NIH/3T3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with Galectin 3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundGalectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of β1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn's disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 26 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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