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Anti-AMPK beta 1 Antibody (6A384)
😃Good
Catalog No. TMAB-02531
Anti-AMPK beta 1 Antibody (6A384) is a Rabbit antibody targeting AMPK beta 1. Anti-AMPK beta 1 Antibody (6A384) can be used in WB,FCM.
Anti-AMPK beta 1 Antibody (6A384)
Anti-AMPK beta 1 Antibody (6A384)
😃Good
Catalog No. TMAB-02531
Anti-AMPK beta 1 Antibody (6A384) is a Rabbit antibody targeting AMPK beta 1. Anti-AMPK beta 1 Antibody (6A384) can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-AMPK beta 1 Antibody (6A384) is a Rabbit antibody targeting AMPK beta 1. Anti-AMPK beta 1 Antibody (6A384) can be used in WB,FCM. |
| Ig Type | IgG |
| Clone | 6A384 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Tissue Specificity | Highly expressed in kidney, heart, white adipose tissue, lung and spleen. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. |
| Immunogen | A synthesized peptide: human AMPK beta 1 |
| Antigen Species | Human |
| Gene Name | PRKAB1 |
| Gene ID | |
| Protein Name | 5'-AMP-activated protein kinase subunit beta-1 |
| Uniprot ID | |
| Function | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). |
| Molecular Weight | Theoretical: 30 kDa. Actual: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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