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Synonyms: Tyrosine-protein kinase-like 7, PTK7, PTK 7, Pseudo tyrosine kinase receptor 7, Protein-tyrosine kinase 7, Inactive tyrosine-protein kinase 7, Colon carcinoma kinase 4 (CCK-4), CCK-4, CCK4, CCK 4


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $74 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human PTK7, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-PTK7 Antibody, hFc Avi Tag with the EC50 of 24.2 ng/ml determined by ELISA (QC Test). |
| Description | PTK7/CCK4 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q13308-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc (IgG1) |
| Accession Number | Q13308-1 |
| Construction | Ala31-Thr704 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Tyrosine-protein kinase-like 7, PTK7, PTK 7, Pseudo tyrosine kinase receptor 7, Protein-tyrosine kinase 7, Inactive tyrosine-protein kinase 7, Colon carcinoma kinase 4 (CCK-4), CCK-4, CCK4, CCK 4 |
| Research Background | Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling. |
| Molecular Weight | 100.56 kDa (Predicted); 110-130 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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