Activity has not been tested. It is theoretically active, but we cannot guarantee it.

CCRK Protein, Mouse, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is Q9JHU3.

Mouse

Baculovirus-Insect Cells

Cyclin-dependent kinase 20,Cdk20,Cdch,Ccrk,CAK-kinase p42

Recombinant full length mouse CDK20 (CCRK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

>75% as determined by SDS-PAGE.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CDK20 or cyclin-dependent kinase 20 contains a kinase domain most closely related to the cyclin-dependent protein kinases which may activate cyclin-dependent kinase 2 and is involved in cell growth. CDK20 is a monomeric CAK that specifically phosphorylates CDK2 thr160 and functions as a CDK2-activating kinase. CDK20 is also a novel cyclin-dependent kinase-activating kinase in mammalian cells. CDK20 depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.