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Synonyms: TMPY-04727, TMPY-01073, RG-1, RG1, RG 1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGFBPTGF-b, PTGF-beta, PTGF-b, PTGFB, Placental TGF-β, Placental TGF-beta, Placental TGF-b, PLAB, PDF, NAG-1, NAG1, NAG 1, MIC-1, MIC1, MIC 1, growth differentiation factor 15, GDF-15, GDF15, GDF 15


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $81 | 7-10 days | 7-10 days | |
| 10 µg | $123 | 7-10 days | 7-10 days | |
| 20 µg | $193 | 7-10 days | 7-10 days | |
| 50 µg | $348 | 7-10 days | 7-10 days | |
| 100 µg | $553 | 7-10 days | 7-10 days | |
| 200 µg | $878 | 7-10 days | 7-10 days | |
| 500 µg | $1,630 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human GDF15 (H202D), His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 16.9 ng/ml determined by ELISA (QC Test). |
| Description | GDF-15 Protein, Human, Recombinant (H202D, His) is expressed in E. coli. The accession number is Q99988. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-His |
| Accession Number | Q99988 |
| Construction | Ala197-Ile308 (H202D) |
| Protein Purity | > 95% as determined by Bis-Tris PAGE |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in 50 mM HAc (pH 2.9). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in 50 mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TMPY-04727, TMPY-01073, RG-1, RG1, RG 1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGFBPTGF-b, PTGF-beta, PTGF-b, PTGFB, Placental TGF-β, Placental TGF-beta, Placental TGF-b, PLAB, PDF, NAG-1, NAG1, NAG 1, MIC-1, MIC1, MIC 1, growth differentiation factor 15, GDF-15, GDF15, GDF 15 |
| Research Background | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |
| Molecular Weight | 13.36 kDa (Predicted); 15-16 kDa (Reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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