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Anti-Tropomyosin Antibody (8B20)

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Catalog No. TMAB-13836

Anti-Tropomyosin Antibody (8B20) is a Rabbit antibody targeting Tropomyosin. Anti-Tropomyosin Antibody (8B20) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.

Anti-Tropomyosin Antibody (8B20)

Anti-Tropomyosin Antibody (8B20)

😃Good
Catalog No. TMAB-13836
Anti-Tropomyosin Antibody (8B20) is a Rabbit antibody targeting Tropomyosin. Anti-Tropomyosin Antibody (8B20) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Tropomyosin Antibody (8B20) is a Rabbit antibody targeting Tropomyosin. Anti-Tropomyosin Antibody (8B20) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
Clone
8B20
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytoskeleton.
Tissue SpecificityDetected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients. Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundBinds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.
Antigen Details
Immunogen
A synthesized peptide: human Tropomyosin 1
Antigen Species
Human
Gene Name
TPM1
Gene ID
Protein Name
Tropomyosin alpha-1 chainTPM1 TPM1 TPM1 Tropomyosin alpha-1 chain
Uniprot ID
Function
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Chemical Properties
Molecular WeightTheoretical: 33 kDa. Actual: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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