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Anti-Bak Antibody (3J180)
😃Good
Catalog No. TMAB-03021
Anti-Bak Antibody (3J180) is a Rabbit antibody targeting Bak. Anti-Bak Antibody (3J180) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Anti-Bak Antibody (3J180)
Anti-Bak Antibody (3J180)
😃Good
Catalog No. TMAB-03021
Anti-Bak Antibody (3J180) is a Rabbit antibody targeting Bak. Anti-Bak Antibody (3J180) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Bak Antibody (3J180) is a Rabbit antibody targeting Bak. Anti-Bak Antibody (3J180) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 3J180 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM=1 μg/Test; ICC/IF=1:100-500; IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion membrane. |
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. |
| Immunogen | A synthesized peptide: human BAK1 |
| Antigen Species | Human |
| Gene Name | BAK1 |
| Gene ID | |
| Protein Name | Bcl-2 homologous antagonist/killer |
| Uniprot ID | |
| Function | In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. |
| Molecular Weight | Theoretical: 23 kDa. Actual: 23 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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