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Synonyms: TPO-R, MPLV, MPL, K12, c-Mpl, CD110


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $129 | 7-10 days | 7-10 days | |
| 20 µg | $196 | 7-10 days | 7-10 days | |
| 50 µg | $365 | 7-10 days | 7-10 days | |
| 100 µg | $577 | 7-10 days | 7-10 days | |
| 200 µg | $918 | 7-10 days | 7-10 days | |
| 500 µg | $1,700 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | C-MPL/TPO-R Protein, Canine, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_038543911.1. |
| Species | Canine |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | XP_038543911.1 |
| Construction | Gln22-Trp489 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | TPO-R, MPLV, MPL, K12, c-Mpl, CD110 |
| Research Background | The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML. |
| Molecular Weight | 54.45 kDa (Predicted); 65-75 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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