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Anti-ULBP1 Antibody (9B852)
😃Good
Catalog No. TMAB-13987
Anti-ULBP1 Antibody (9B852) is a Rabbit antibody targeting ULBP1. Anti-ULBP1 Antibody (9B852) can be used in WB.
Anti-ULBP1 Antibody (9B852)
Anti-ULBP1 Antibody (9B852)
😃Good
Catalog No. TMAB-13987
Anti-ULBP1 Antibody (9B852) is a Rabbit antibody targeting ULBP1. Anti-ULBP1 Antibody (9B852) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ULBP1 Antibody (9B852) is a Rabbit antibody targeting ULBP1. Anti-ULBP1 Antibody (9B852) can be used in WB. |
| Ig Type | IgG |
| Clone | 9B852 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. Note=Detected intracellularly in the endoplasmic reticulum of CMV-infected fibroblasts. |
| Tissue Specificity | Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
| Immunogen | A synthesized peptide: human ULBP1 |
| Antigen Species | Human |
| Gene Name | ULBP1 |
| Gene ID | |
| Protein Name | UL16-binding protein 1 |
| Uniprot ID | |
| Function | Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. |
| Molecular Weight | Theoretical: 28 kDa. Actual: 36 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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