ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated

Name: ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
Brand: TargetMol
SKU: TMPK-01588
Rating: 4.5 (1 reviews)

(Synonyms: ACVR2B, ActRIIB, Activin RIIB, Activin receptor type-2B) Copy Product Info

Synonyms: ACVR2B, ActRIIB, Activin RIIB, Activin receptor type-2B

Catalog No. TMPK-01588 Copy Product Info

ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus).

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Pack Size	Price	USA Stock	Global Stock
5 µg	$108	7-10 days	7-10 days
10 µg	$169	7-10 days	7-10 days
20 µg	$267	7-10 days	7-10 days
50 µg	$488	7-10 days	7-10 days
100 µg	$776	7-10 days	7-10 days
200 µg	$1,230	7-10 days	7-10 days
500 µg	$2,290	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human Activin A, No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 20.9 ng/ml determined by ELISA (QC Test).
Description	ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus).
Species	Human/Cynomolgus
Expression System	HEK293 Cells
Tag	C-hFc (IgG1)-Avi
Accession Number	Q13705-1(Human)/XP_045242398.1(Cynomolgus)
Construction	Ser19-Thr137 (Human)/Ser40-Thr158 (Cynomolgus)
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	ACVR2B, ActRIIB, Activin RIIB, Activin receptor type-2B
Research Background	ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).

Chemical Properties

Molecular Weight

41.41 kDa (Predicted); 55-70 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Dose Conversion

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Related Tags: ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated chemical structure | ACVR2B Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated molecular weight