ALK-1 Protein, Human, Recombinant (GST)

Catalog No. TMPC-00020 Copy Product Info

ALK-1 Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P37023.

ALK-1 Protein, Human, Recombinant (GST)

Catalog No. TMPC-00020

Copy Product Info

ALK-1 Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P37023.

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10 μg	$1,390	Inquiry	Inquiry

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

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Biological Activity	Representative specific activity data for ALK1 were obtained using different assay formats: - 20-25 nmol/min/mg, determined by radioactive kinase assay - 2.8-3.4 nmol/min/mg, determined by ADP-Glo kinase assay Different lots may be tested using different assay methods; therefore, values obtained using different assay formats are not directly comparable.
Description	ALK-1 Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P37023.
Species	Human
Expression System	Baculovirus-Insect Cells
Tag	N-GST
Accession Number	P37023
Synonyms	TSR-I,SKR3,ALK-1,ALK1,ACVRLK1,ACVRL1,Activin receptor type-1-like
Construction	Recombinant human ALK1 (144-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Protein Purity	>70% as determined by SDS-PAGE.
Molecular Weight	~64 kDa
Formulation	Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Research Background	Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.