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Anti-EYA2 Antibody (9O644)
😃Good
Catalog No. TMAB-05761
Anti-EYA2 Antibody (9O644) is a Rabbit antibody targeting EYA2. Anti-EYA2 Antibody (9O644) can be used in WB.
Anti-EYA2 Antibody (9O644)
Anti-EYA2 Antibody (9O644)
😃Good
Catalog No. TMAB-05761
Anti-EYA2 Antibody (9O644) is a Rabbit antibody targeting EYA2. Anti-EYA2 Antibody (9O644) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-EYA2 Antibody (9O644) is a Rabbit antibody targeting EYA2. Anti-EYA2 Antibody (9O644) can be used in WB. |
| Ig Type | IgG |
| Clone | 9O644 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Highest expression in muscle with lower levels in kidney, placenta, pancreas, brain and heart. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. |
| Immunogen | A synthesized peptide: human EYA2 |
| Antigen Species | Human |
| Gene Name | EYA2 |
| Gene ID | |
| Protein Name | Eyes absent homolog 2 |
| Uniprot ID | |
| Function | Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1. Seems to coactivate SIX2, SIX4 and SIX5. Together with SIX1 and DACH2 seem to be involved in myogenesis. May be involved in development of the eye. Interaction with GNAZ and GNAI2 prevents nuclear translocation and transcriptional activity. |
| Molecular Weight | Theoretical: 59 kDa. Actual: 60 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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