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Anti-TYMS Antibody (5D281)
Catalog No. TMAB-13910 Copy Product Info
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Anti-TYMS Antibody (5D281) is a Mouse antibody targeting TYMS. Anti-TYMS Antibody (5D281) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TYMS Antibody (5D281)
Copy Product Info🥰Excellent
Catalog No. TMAB-13910
Anti-TYMS Antibody (5D281) is a Mouse antibody targeting TYMS. Anti-TYMS Antibody (5D281) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TYMS Antibody
(5D281)
(5D281)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TYMS Antibody (5D281) is a Mouse antibody targeting TYMS. Anti-TYMS Antibody (5D281) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1, Kappa |
| Clone | 5D281 |
| Reactivity | Human |
| Verified Activity | 1. Tissue: Human colon cancer Section type: Formalin fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:100 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for TMAB-13910 2. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 4℃overnight Lysate: 293, Jurkat, HeLa, HepG2 Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 36 kDa Observed MW: 35 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane. |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017] |
| Gene Name | TYMS |
| Gene ID | |
| Protein Name | Thymidylate synthase |
| Function | Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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