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Anti-Netrin 1 Antibody (6P616)
😃Good
Catalog No. TMAB-09365
Anti-Netrin 1 Antibody (6P616) is a Rabbit antibody targeting Netrin 1. Anti-Netrin 1 Antibody (6P616) can be used in WB,ICC/IF.
Anti-Netrin 1 Antibody (6P616)
Anti-Netrin 1 Antibody (6P616)
😃Good
Catalog No. TMAB-09365
Anti-Netrin 1 Antibody (6P616) is a Rabbit antibody targeting Netrin 1. Anti-Netrin 1 Antibody (6P616) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Netrin 1 Antibody (6P616) is a Rabbit antibody targeting Netrin 1. Anti-Netrin 1 Antibody (6P616) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 6P616 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. |
| Immunogen | A synthesized peptide: human Netrin 1 |
| Antigen Species | Human |
| Gene Name | NTN1 |
| Gene ID | |
| Protein Name | Netrin-1 |
| Uniprot ID | |
| Function | Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis. |
| Molecular Weight | Theoretical: 68 kDa. Actual: 75 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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