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Anti-PU.1/Spi1 Antibody (3K631)
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Catalog No. TMAB-11943
Anti-PU.1/Spi1 Antibody (3K631) is a Rabbit antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (3K631) can be used in WB.
Anti-PU.1/Spi1 Antibody (3K631)
Anti-PU.1/Spi1 Antibody (3K631)
😃Good
Catalog No. TMAB-11943
Anti-PU.1/Spi1 Antibody (3K631) is a Rabbit antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (3K631) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PU.1/Spi1 Antibody (3K631) is a Rabbit antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (3K631) can be used in WB. |
| Ig Type | IgG |
| Clone | 3K631 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions. |
| Immunogen | A synthesized peptide: human SPI1 |
| Antigen Species | Human |
| Gene Name | SPI1 |
| Gene ID | |
| Protein Name | Transcription factor PU.1 |
| Uniprot ID | |
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
| Molecular Weight | Theoretical: 31 kDa. Actual: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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