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Anti-PU.1/Spi1 Antibody (3K631)
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Catalog No. TMAB-11943 Copy Product Info
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Anti-PU.1/Spi1 Antibody (3K631) is a Rabbit antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (3K631) can be used in WB.
Anti-PU.1/Spi1 Antibody
(3K631)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 µL | $148 | 7-10 days | 7-10 days | |
| 50 µL | $264 | 7-10 days | 7-10 days | |
| 100 µL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-PU.1/Spi1 Antibody (3K631) is a Rabbit antibody targeting PU.1/Spi1. Anti-PU.1/Spi1 Antibody (3K631) can be used in WB. |
| Ig Type | IgG |
| Clone | 3K631 |
| Reactivity | Human,Mouse |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with PU.1/Spi1 monoclonal antibody, unconjugated (TMAB-11943) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions. |
| Immunogen | A synthesized peptide: human SPI1 |
| Antigen Species | Human |
| Gene Name | SPI1 |
| Gene ID | |
| Protein Name | Transcription factor PU.1 |
| Uniprot ID | |
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. |
| Molecular Weight | Theoretical: 31 kDa. Actual: 42 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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