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Anti-NRG3 Antibody (2R421)
😃Good
Catalog No. TMAB-09638
Anti-NRG3 Antibody (2R421) is a Rabbit antibody targeting NRG3. Anti-NRG3 Antibody (2R421) can be used in FCM.
Anti-NRG3 Antibody (2R421)
Anti-NRG3 Antibody (2R421)
😃Good
Catalog No. TMAB-09638
Anti-NRG3 Antibody (2R421) is a Rabbit antibody targeting NRG3. Anti-NRG3 Antibody (2R421) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-NRG3 Antibody (2R421) is a Rabbit antibody targeting NRG3. Anti-NRG3 Antibody (2R421) can be used in FCM. |
| Ig Type | IgG |
| Clone | 2R421 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Pro-neuregulin-3, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein. Neuregulin-3: Secreted. Isoform 3: Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes. |
| Immunogen | A synthesized peptide: human NRG3 |
| Antigen Species | Human |
| Gene Name | NRG3 |
| Gene ID | |
| Protein Name | Pro-neuregulin-3, membrane-bound isoform |
| Uniprot ID | |
| Function | Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes. |
| Molecular Weight | Theoretical: 78 kDa. Actual: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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