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Anti-AGO3 Antibody (9X939) is an antibody targeting AGO3. Anti-AGO3 Antibody (9X939) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Anti-AGO3 Antibody (9X939) is an antibody targeting AGO3. Anti-AGO3 Antibody (9X939) can be used in ELISA. |
Alias | EIF2C3, argonaute RISC catalytic component 3 |
Ig Type | Rabbit IgG |
Clone | 9X939 |
Reactivity | Human |
Application | ELISA |
Antibody Type | Monoclonal |
Subcellular Localization | Cytoplasm, P-body. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human AGO3 |
Antigen Species | Human |
Gene ID | 192669 |
Uniprot ID | |
Biology Area | Epigenetics and Nuclear Signaling |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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