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B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His)
(Synonyms: CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3) Copy Product InfoSynonyms: CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3
Catalog No. TMPY-02031U Copy Product Info
B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q5ZPR3-1.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $36 | 7-10 days | 7-10 days | |
| 10 µg | $55 | 7-10 days | 7-10 days | |
| 20 µg | $86 | 7-10 days | 7-10 days | |
| 50 µg | $163 | 7-10 days | 7-10 days | |
| 100 µg | $272 | 7-10 days | 7-10 days | |
| 200 µg | $481 | 7-10 days | 7-10 days | |
| 500 µg | $1,020 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human B7-H3 (4Ig), His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 5.0 ng/ml determined by ELISA. (QC Test) Loaded Anti-B7-H3 Ab, hFc Tag on ProA-Biosensor can bind Human B7-H3 (4Ig), His Tag with an affinity constant of 4.59 nM as determined in BLI assay . |
| Description | B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q5ZPR3-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q5ZPR3-1 |
| Construction | Gly27-Thr461 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 0.1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3 |
| Research Background | B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. |
| Molecular Weight | 48.25 kDa (Predicted); 68-78 kDa (Due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) chemical structure | B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) molecular weight
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