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Anti-TRPM8 Antibody (5G328)
😃Good
Catalog No. TMAB-13847
Anti-TRPM8 Antibody (5G328) is a Rabbit antibody targeting TRPM8. Anti-TRPM8 Antibody (5G328) can be used in WB.
Anti-TRPM8 Antibody (5G328)
Anti-TRPM8 Antibody (5G328)
😃Good
Catalog No. TMAB-13847
Anti-TRPM8 Antibody (5G328) is a Rabbit antibody targeting TRPM8. Anti-TRPM8 Antibody (5G328) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TRPM8 Antibody (5G328) is a Rabbit antibody targeting TRPM8. Anti-TRPM8 Antibody (5G328) can be used in WB. |
| Ig Type | IgG |
| Clone | 5G328 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein (Probable). |
| Tissue Specificity | Expressed in prostate. Also expressed in most in prostate tumors. Also expressed in non-prostatic primary tumors such as colon, lung, breast and skin tumors. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. |
| Immunogen | A synthesized peptide: human TRPM8 |
| Antigen Species | Human |
| Gene Name | TRPM8 |
| Gene ID | |
| Protein Name | Transient receptor potential cation channel subfamily M member 8 |
| Uniprot ID | |
| Function | Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing. |
| Molecular Weight | Theoretical: 128 kDa. Actual: 128 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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