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Anti-CD33 Antibody (6P608)

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Catalog No. TMAB-03957

Anti-CD33 Antibody (6P608) is a Rabbit antibody targeting CD33. Anti-CD33 Antibody (6P608) can be used in IHC-P,WB,IHC-Fr,IF.

Anti-CD33 Antibody (6P608)

Anti-CD33 Antibody (6P608)

😃Good
Catalog No. TMAB-03957
Anti-CD33 Antibody (6P608) is a Rabbit antibody targeting CD33. Anti-CD33 Antibody (6P608) can be used in IHC-P,WB,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD33 Antibody (6P608) is a Rabbit antibody targeting CD33. Anti-CD33 Antibody (6P608) can be used in IHC-P,WB,IHC-Fr,IF.
Ig Type
IgG
Clone
6P608
Reactivity
Human
Application
Recommended Dose
IHC-P: 1:100-500; WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein.
Tissue SpecificityMonocytic/myeloid lineage cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEnables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
Antigen Details
Immunogen
A synthesized peptide: human CD33
Antigen Species
Human
Gene Name
CD33
Gene ID
Protein Name
Myeloid cell surface antigen CD33
Uniprot ID
Function
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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